Patch Bio engineers expression for genetic medicine. We build technology to make RNA therapeutics and gene therapies live up to their promise, moving past the few initial cases where they are now deployed to power dozens, even hundreds of therapeutics.
For this to happen, the nucleic acids delivered into the body must be expressed as intended, in just the right place and in just the right way. But there is a blocker: the way to encode these properties into genetic medicines is unknown. The language of gene regulation is only beginning to be understood.
To crack this code we work at the interface of genomics, machine learning, and synthetic biology. Help us figure out this puzzle and engineer better genetic medicines — our pharma partners, and tens of millions of patients, need it.
Your mission is to engineer DNA/RNA regulatory elements with particular properties, so that they can enable our partners’ genetic medicines.
To do this, you will work in tandem with a molecular biologist: together, you will be responsible for one of our preclinical programs, which today include mRNA, gene editing, and gene therapy modalities.
You will leverage our AI and genomics platform, and collaborate with the broader team of scientists and engineers at Patch. You will contribute to sequence design and experiment planning. You will conduct in-depth analyses of our data, make connections with known biology, and also push forward our platform by improving our computational pipelines.
And with all this, you will engineer sequences that will enable new genetic medicines.
There is much to discover, so we must learn rapidly. Our core values help us achieve this. We value adaptability; high standards for scientific quality; effective communication; a focus on outcomes over processes; and the willingness to fail. Lastly, and perhaps more importantly, we value kindness in everyday interaction.